At the beginning, we see the Road Runner, known as Boulevardius Burnupius, giving Wile E. a “come-on” to chase him, and the camera moves to Wile and freezes to show he is Dogius Ignoramii for this cartoon. The chase continues until the coyote stops to read a sign in the road: “WARNING: The Surgeon General has determined that chasing Road Runners may be hazardous to your health.” He dismisses this sign as cheesy and laughs at it, before the Road Runner pulls up behind him and beeps the coyote into another headache. Within the outcropping, Wile recovers and sees another sign posted at the very end of the outcropping: “It’s not cool to laugh at the Surgeon General.”